|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007452,
umls-concept:C0009015,
umls-concept:C0017262,
umls-concept:C0025344,
umls-concept:C0029939,
umls-concept:C0035696,
umls-concept:C0072978,
umls-concept:C0185117,
umls-concept:C0851285,
umls-concept:C1561960,
umls-concept:C1948053,
umls-concept:C2347804,
umls-concept:C2911684
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2000-2-3
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
RANTES may be one of the chemoattractants involved in stimulating eosinophils and macrophages to migrate selectively into bovine dominant follicles and into developing corpora lutea. We sequenced a 736 bp fragment of the bovine RANTES mRNA encoding the complete protein and defined the ovarian source of RANTES mRNA. As demonstrated by competitive RT-PCR, follicle-derived macrophages showed a 100-1000 times higher RANTES mRNA level compared to unpurified granulosa cells or follicle-derived fibroblasts. By means of in situ hybridization, RANTES mRNA positive macrophages were located in the former thecal layer of the developing corpora lutea.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0014-5793
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
10
|
|
pubmed:volume |
463
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
160-4
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10601659-Amino Acid Sequence,
pubmed-meshheading:10601659-Animals,
pubmed-meshheading:10601659-Base Sequence,
pubmed-meshheading:10601659-Cattle,
pubmed-meshheading:10601659-Cells, Cultured,
pubmed-meshheading:10601659-Chemokine CCL5,
pubmed-meshheading:10601659-Cloning, Molecular,
pubmed-meshheading:10601659-DNA, Complementary,
pubmed-meshheading:10601659-Eosinophils,
pubmed-meshheading:10601659-Female,
pubmed-meshheading:10601659-Granulosa Cells,
pubmed-meshheading:10601659-In Situ Hybridization,
pubmed-meshheading:10601659-Macrophages,
pubmed-meshheading:10601659-Molecular Sequence Data,
pubmed-meshheading:10601659-Ovary,
pubmed-meshheading:10601659-Ovulation,
pubmed-meshheading:10601659-RNA, Messenger,
pubmed-meshheading:10601659-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10601659-Up-Regulation
|
|
pubmed:year |
1999
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|
pubmed:articleTitle |
Cloning of bovine RANTES mRNA and its expression and regulation in ovaries in the periovulatory period.
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|
pubmed:affiliation |
Institute of Anatomy, University of Leipzig, Liebigstrasse 13, Leipzig, Germany. ausg@medizin.uni-leipzig.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
