rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
21
|
pubmed:dateCreated |
1999-12-9
|
pubmed:abstractText |
4-Chlorophenylmethanesulfonamide and (4-chlorobenzyl)sulfamide derivatives of histamine homologues were prepared and found to be potent and selective histamine H3 receptor antagonists. High receptor affinity and low differences in the data from the bioassays were achieved with the imidazol-4-ylbutyl analogues.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0960-894X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3103-8
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:10560733-Animals,
pubmed-meshheading:10560733-Drug Design,
pubmed-meshheading:10560733-Guinea Pigs,
pubmed-meshheading:10560733-Histamine,
pubmed-meshheading:10560733-Histamine Antagonists,
pubmed-meshheading:10560733-Ileum,
pubmed-meshheading:10560733-Molecular Structure,
pubmed-meshheading:10560733-Muscle Contraction,
pubmed-meshheading:10560733-Naphthalenes,
pubmed-meshheading:10560733-Receptors, Histamine H3,
pubmed-meshheading:10560733-Sulfonamides
|
pubmed:year |
1999
|
pubmed:articleTitle |
4-Chlorobenzyl sulfonamide and sulfamide derivatives of histamine homologues: the design of potent histamine H3 receptor antagonists.
|
pubmed:affiliation |
The James Black Foundation, London, UK. matthew.tozer@kcl.ac.uk
|
pubmed:publicationType |
Journal Article
|