Linked Life Data

10560015

Source:http://linkedlifedata.com/resource/pubmed/id/10560015

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-12-2
pubmed:abstractText
The endocrine pancreas of four reptile species belonging to the turtles, lizards and snakes was investigated immunohistochemically for the occurrence and cellular distribution of chromogranin A (CgA) and of two synthetic secretonin II (SgII)-peptides (C23-3 and C26-3). CgA-immunoreactivity was found only in the turtle pancreas, whereas that for SGIIC23-3 appeared both in the turtle and snake. None of the species studied displayed immunoreactivity for SgIIC26-3. The two detected granins showed different distributions in relation to the endocrine cell types. Conspicuous variations of the immunostaining density for either granin in the same endocrine cell population and even complete lack of the immunoreaction were recorded. The findings suggest that, despite the restricted presence in the endocrine pancreas of the reptiles investigated, the granins are relatively well conserved during phylogeny; they do not confirm, however, the previously accepted usefulness of the granin protein family as common markers of neuroendocrine cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0940-9602
pubmed:author
pubmed:issnType
Print
pubmed:volume
181
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
489-94
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Granin proteins (chromogranin A and secretogranin II C23-3 and C26-3) in the endocrine pancreas of reptiles.
pubmed:affiliation
Department of Comparative Endocrinology, Institute of Biology, Bucharest, Romania.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't