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rdf:type |
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lifeskim:mentions |
umls-concept:C0028128,
umls-concept:C0031727,
umls-concept:C0033268,
umls-concept:C0035820,
umls-concept:C0086418,
umls-concept:C0225369,
umls-concept:C0521447,
umls-concept:C0752312,
umls-concept:C0851285,
umls-concept:C1521761,
umls-concept:C1979930
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pubmed:issue |
11
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pubmed:dateCreated |
1999-11-22
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pubmed:abstractText |
To explore the signaling pathways by which the proinflammatory cytokine interleukin-17 (IL-17) may contribute to cartilage catabolism in osteoarthritis (OA) by inducing inducible nitric oxide synthase (iNOS) expression in chondrocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-17,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NOS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Ribosomal Protein S6 Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Ribosomal Protein S6 Kinases, 90-kDa
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2399-409
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:10555036-Aged,
pubmed-meshheading:10555036-Cells, Cultured,
pubmed-meshheading:10555036-Chondrocytes,
pubmed-meshheading:10555036-Enzyme Activation,
pubmed-meshheading:10555036-Female,
pubmed-meshheading:10555036-Humans,
pubmed-meshheading:10555036-Interleukin-17,
pubmed-meshheading:10555036-Male,
pubmed-meshheading:10555036-Mitogen-Activated Protein Kinases,
pubmed-meshheading:10555036-NF-kappa B,
pubmed-meshheading:10555036-Nitric Oxide,
pubmed-meshheading:10555036-Nitric Oxide Synthase,
pubmed-meshheading:10555036-Nitric Oxide Synthase Type II,
pubmed-meshheading:10555036-Osteoarthritis,
pubmed-meshheading:10555036-Ribosomal Protein S6 Kinases,
pubmed-meshheading:10555036-Ribosomal Protein S6 Kinases, 90-kDa,
pubmed-meshheading:10555036-Signal Transduction,
pubmed-meshheading:10555036-Transcriptional Activation
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pubmed:year |
1999
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pubmed:articleTitle |
Mitogen-activated protein kinase and nuclear factor kappaB together regulate interleukin-17-induced nitric oxide production in human osteoarthritic chondrocytes: possible role of transactivating factor mitogen-activated protein kinase-activated proten kinase (MAPKAPK).
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pubmed:affiliation |
Centre Hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Quebec, Canada.
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pubmed:publicationType |
Journal Article
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