Source:http://linkedlifedata.com/resource/pubmed/id/10535608
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-11-18
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pubmed:abstractText |
Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results suggest a significant increase serum TNF-alpha in patients with CFS (P<0.0001) compared to non-CFS controls. This study supports the further examination of the role of proinflammatory mediators in CFS. Furthermore, the clinical testing of TNF-alpha blockers and other antiinflammatory agents for the treatment of this disease is warranted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0271-9142
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10535608-Adult,
pubmed-meshheading:10535608-Aged,
pubmed-meshheading:10535608-Cross-Sectional Studies,
pubmed-meshheading:10535608-Fatigue Syndrome, Chronic,
pubmed-meshheading:10535608-Female,
pubmed-meshheading:10535608-Humans,
pubmed-meshheading:10535608-Male,
pubmed-meshheading:10535608-Middle Aged,
pubmed-meshheading:10535608-Retrospective Studies,
pubmed-meshheading:10535608-Tumor Necrosis Factor-alpha
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pubmed:year |
1999
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pubmed:articleTitle |
TNF-alpha and chronic fatigue syndrome.
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pubmed:affiliation |
The Immune Response Corporation, Carlsbad, California 92008, USA. shotdoc@imnr.com
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pubmed:publicationType |
Journal Article
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