|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0012854,
umls-concept:C0013018,
umls-concept:C0019737,
umls-concept:C0019751,
umls-concept:C0023746,
umls-concept:C0030705,
umls-concept:C0033204,
umls-concept:C0332307,
umls-concept:C0441889,
umls-concept:C0445356,
umls-concept:C0680844,
umls-concept:C0681916,
umls-concept:C0750572,
umls-concept:C1415561,
umls-concept:C1415562,
umls-concept:C1521991,
umls-concept:C1527178,
umls-concept:C1705938,
umls-concept:C1708943
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
1999-11-19
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|
pubmed:abstractText |
Recent evidence suggests a more significant role of HLA-C as a target of alloreactions after bone marrow transplantation than previously suspected. Although linkage disequilibrium (LD) between HLA-B and -C serogroups is well documented, the level of LD at the allelic level is not known. In this study, we determine the LD between HLA-B and -C alleles and estimate the probability of molecular HLA-C matching between unrelated individuals who match for both HLA-B alleles.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0041-1337
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
|
pubmed:volume |
68
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1044-50
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10532548-Alleles,
pubmed-meshheading:10532548-Bone Marrow Transplantation,
pubmed-meshheading:10532548-DNA,
pubmed-meshheading:10532548-Gene Frequency,
pubmed-meshheading:10532548-HLA-B Antigens,
pubmed-meshheading:10532548-HLA-C Antigens,
pubmed-meshheading:10532548-Haplotypes,
pubmed-meshheading:10532548-Histocompatibility Testing,
pubmed-meshheading:10532548-Humans,
pubmed-meshheading:10532548-Linkage Disequilibrium,
pubmed-meshheading:10532548-Polymerase Chain Reaction,
pubmed-meshheading:10532548-Probability,
pubmed-meshheading:10532548-Tissue Donors
|
|
pubmed:year |
1999
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|
pubmed:articleTitle |
The probability of HLA-C matching between patient and unrelated donor at the molecular level: estimations based on the linkage disequilibrium between DNA typed HLA-B and HLA-C alleles.
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|
pubmed:affiliation |
Department of Pediatrics, Biochemical Immunogenetics Laboratory, Memorial Sloan Kettering Cancer Center, New York 10021, USA. prasadv@mskcc.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|
