Linkage Disequilibrium

Source:http://linkedlifedata.com/resource/umls/id/C0023746

MSH: Nonrandom association of linked genes. This is the tendency of the alleles of two separate but already linked loci to be found together more frequently than would be expected by chance alone.,CSP: when a specific haplotype is almost always associated with a gene mutation; genetic diagnostic method used to decrease uncertainty in linkage analysis.,NCI: Where alleles (DNA markers) occur together more often than can be accounted for by chance because of their physical proximity on a chromosome.,NCI: Nonrandom association of linked genes; the occurrence of some genes together, more often than would be expected based upon their physical separation, presumably because the combination confers some selective advantage.

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