Source:http://linkedlifedata.com/resource/pubmed/id/10479163
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1999-11-8
|
| pubmed:abstractText |
A random sample of 960 women aged 15-59 years enrolled in a population-based study in rural Uganda were asked to provide self-collected vaginal swabs for human papillomavirus (HPV) testing by hybrid capture assay. The intensity of HPV infection was assessed by the relative light unit (RLU) ratio in the specimen-to-positive control (PC) ratio. In total, 898 women (93%) provided a swab and 737 provided serum for human immunodeficiency virus type 1 (HIV-1) determination. HPV prevalence was 16.7% and was highest in younger women. HIV-1 prevalence was 17.8%. HPV prevalence was 44.3% in HIV-positive and 10.2% in HIV-negative women (rate ratio, 5.36; 95% confidence interval, 3.81-7.54). The intensity of HPV infection was significantly greater among HIV-positive than HIV-negative women (54. 4 vs. 11.1 RLU/PC; P=.026); intensity of infection was highest in women aged <30 years. The higher prevalence and intensity of HPV infection in HIV-positive women could facilitate HPV transmission in this population. Self-collected vaginal swabs could be used in population-based screening to identify women at high risk of cervical neoplasia.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0022-1899
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
180
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1316-9
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:10479163-Adolescent,
pubmed-meshheading:10479163-Adult,
pubmed-meshheading:10479163-Age Factors,
pubmed-meshheading:10479163-Case-Control Studies,
pubmed-meshheading:10479163-Confidence Intervals,
pubmed-meshheading:10479163-Female,
pubmed-meshheading:10479163-HIV Seropositivity,
pubmed-meshheading:10479163-HIV Seroprevalence,
pubmed-meshheading:10479163-HIV-1,
pubmed-meshheading:10479163-Humans,
pubmed-meshheading:10479163-Papillomaviridae,
pubmed-meshheading:10479163-Papillomavirus Infections,
pubmed-meshheading:10479163-Prevalence,
pubmed-meshheading:10479163-Rural Health,
pubmed-meshheading:10479163-Rural Population,
pubmed-meshheading:10479163-Sexually Transmitted Diseases,
pubmed-meshheading:10479163-Tumor Virus Infections,
pubmed-meshheading:10479163-Uganda,
pubmed-meshheading:10479163-Vaginal Smears
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Use of a hybrid capture assay of self-collected vaginal swabs in rural Uganda for detection of human papillomavirus.
|
| pubmed:affiliation |
Institute of Public Health, Faculty of Medicine, Makerere University, Kampala, Uganda.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|