rdf:type |
|
lifeskim:mentions |
umls-concept:C0002965,
umls-concept:C0005821,
umls-concept:C0030705,
umls-concept:C0039194,
umls-concept:C0167627,
umls-concept:C0441889,
umls-concept:C0699748,
umls-concept:C0948089,
umls-concept:C1314939,
umls-concept:C1749467,
umls-concept:C2349975
|
pubmed:issue |
6
|
pubmed:dateCreated |
1999-9-13
|
pubmed:abstractText |
The CD40 ligand (CD40L) on activated T cells and platelets may be activating matrix metalloproteinases, inducing procoagulant activity, and be involved in the pathogenesis of acute coronary syndromes by promoting plaque rupture in atheroma.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD40,
http://linkedlifedata.com/resource/pubmed/chemical/CD40 Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiovascular Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/thrombin receptor peptide (42-47)
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1524-4539
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
10
|
pubmed:volume |
100
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
614-20
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pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10441098-Acute Disease,
pubmed-meshheading:10441098-Aged,
pubmed-meshheading:10441098-Angina, Unstable,
pubmed-meshheading:10441098-Angina Pectoris,
pubmed-meshheading:10441098-Antigens, CD40,
pubmed-meshheading:10441098-Blood Platelets,
pubmed-meshheading:10441098-CD4-Positive T-Lymphocytes,
pubmed-meshheading:10441098-CD40 Ligand,
pubmed-meshheading:10441098-CD8-Positive T-Lymphocytes,
pubmed-meshheading:10441098-Cardiovascular Agents,
pubmed-meshheading:10441098-Cell Membrane,
pubmed-meshheading:10441098-Chemokine CCL2,
pubmed-meshheading:10441098-Cholesterol,
pubmed-meshheading:10441098-Coronary Disease,
pubmed-meshheading:10441098-Cytoplasmic Granules,
pubmed-meshheading:10441098-Female,
pubmed-meshheading:10441098-Humans,
pubmed-meshheading:10441098-Male,
pubmed-meshheading:10441098-Membrane Glycoproteins,
pubmed-meshheading:10441098-Metalloendopeptidases,
pubmed-meshheading:10441098-Middle Aged,
pubmed-meshheading:10441098-Peptide Fragments,
pubmed-meshheading:10441098-Platelet Activation,
pubmed-meshheading:10441098-Rupture, Spontaneous,
pubmed-meshheading:10441098-Smoking,
pubmed-meshheading:10441098-Solubility,
pubmed-meshheading:10441098-Syndrome,
pubmed-meshheading:10441098-Triglycerides,
pubmed-meshheading:10441098-Vasculitis
|
pubmed:year |
1999
|
pubmed:articleTitle |
Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes.
|
pubmed:affiliation |
Section of Clinical Immunology and Infectious Diseases, Research Institute for Internal Medicine, Department of Cardiology, University of Oslo, Norway.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|