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rdf:type |
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lifeskim:mentions |
umls-concept:C0013138,
umls-concept:C0031516,
umls-concept:C0178499,
umls-concept:C0204727,
umls-concept:C0205309,
umls-concept:C0205409,
umls-concept:C0220806,
umls-concept:C0221102,
umls-concept:C0314603,
umls-concept:C1260875,
umls-concept:C1626935
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pubmed:issue |
16
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pubmed:dateCreated |
1999-9-9
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pubmed:abstractText |
Overexpression of the UAS-tra transgene in Drosophila melanogaster females led to the complete elimination of their cuticular pheromones. According to current models of Drosophila behavior, these flies should induce no courtship. In fact, they are still attractive to conspecific males. Three classes of stimuli are shown to induce courtship, with different effects on male behavior: (i) known pheromones produced by control females, (ii) stimuli produced by living control and transgenic flies, and (iii) as-yet-undetermined pheromones present on both control and transgenic flies. Only the latter class of pheromones are required for mating. They appear to represent a layer of ancestral attractive substances present in D. melanogaster and its sibling species; known cuticular pheromones modulate this attractivity positively or negatively. The absence of inhibitory pheromones leads to high levels of interspecific mating, suggesting an important role for these cuticular hydrocarbons in isolation between species.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-117791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-2748596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-3095835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-6441563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-7707973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-7846534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-8073292,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-8209251,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-8600389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-8690269,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-8851882,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-9093854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-9171057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10430887-9501419
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9015-20
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10430887-Animals,
pubmed-meshheading:10430887-Animals, Genetically Modified,
pubmed-meshheading:10430887-Crosses, Genetic,
pubmed-meshheading:10430887-DNA-Binding Proteins,
pubmed-meshheading:10430887-Drosophila,
pubmed-meshheading:10430887-Drosophila melanogaster,
pubmed-meshheading:10430887-Female,
pubmed-meshheading:10430887-Fungal Proteins,
pubmed-meshheading:10430887-Genotype,
pubmed-meshheading:10430887-HSP70 Heat-Shock Proteins,
pubmed-meshheading:10430887-Hot Temperature,
pubmed-meshheading:10430887-Hydrocarbons,
pubmed-meshheading:10430887-Male,
pubmed-meshheading:10430887-Pheromones,
pubmed-meshheading:10430887-Recombinant Fusion Proteins,
pubmed-meshheading:10430887-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:10430887-Sexual Behavior, Animal,
pubmed-meshheading:10430887-Social Isolation,
pubmed-meshheading:10430887-Transcription Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Genetic elimination of known pheromones reveals the fundamental chemical bases of mating and isolation in Drosophila.
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pubmed:affiliation |
Neurobiologie de l'Apprentissage et de la Memoire Mécanismes de Communication, Centre National de la Recherche Scientifique Unité Mixte de Recherche 8620, Université Paris Sud, 91405 Orsay, France.
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pubmed:publicationType |
Journal Article
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