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rdf:type |
|
|
lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
1999-7-16
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pubmed:abstractText |
Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). TNF-alpha-converting enzyme (TACE) has recently been purified and its complementary DNA cloned. The expression of TACE results in the production of a functional enzyme that has precursor TNF-alpha in the mature form. The aim of this study was to determine whether TACE is expressed with TNF-alpha in myocardium and whether levels of TACE and TNF-alpha are related to clinical severity of DCM.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:day |
29
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pubmed:volume |
99
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3260-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10385500-ADAM Proteins,
pubmed-meshheading:10385500-Adolescent,
pubmed-meshheading:10385500-Adult,
pubmed-meshheading:10385500-Aged,
pubmed-meshheading:10385500-Cardiomyopathy, Dilated,
pubmed-meshheading:10385500-DNA Primers,
pubmed-meshheading:10385500-Female,
pubmed-meshheading:10385500-Gene Expression Regulation,
pubmed-meshheading:10385500-Humans,
pubmed-meshheading:10385500-Immunohistochemistry,
pubmed-meshheading:10385500-Male,
pubmed-meshheading:10385500-Metalloendopeptidases,
pubmed-meshheading:10385500-Middle Aged,
pubmed-meshheading:10385500-RNA, Messenger,
pubmed-meshheading:10385500-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10385500-Severity of Illness Index,
pubmed-meshheading:10385500-Tumor Necrosis Factor-alpha
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pubmed:year |
1999
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pubmed:articleTitle |
Tumor necrosis factor-alpha-converting enzyme and tumor necrosis factor-alpha in human dilated cardiomyopathy.
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pubmed:affiliation |
Second Department of Internal Medicine, Iwate Medical University School of Medicine, Iwate, Japan. staohm@iwate-med.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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