Source:http://linkedlifedata.com/resource/pubmed/id/10355484
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-7-15
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pubmed:abstractText |
Peripheral noradrenergic activity is enhanced in portal hypertension and correlates with the progression of the disease. However, little is known about the status of central norepinephrine (NE) in portal hypertension. The aim of the present work was to study the uptake of NE in several areas rich in NE in experimental prehepatic portal hypertension. The experiments were performed in vitro in several encephalic areas and nuclei, obtained according to the 'punch-out technique'. Results showed that in portal hypertensive rats NE uptake enhanced in all areas and nuclei studies (subfornical organ, organum vasculosum lamina terminalis, area postrema, locus coeruleus and nucleus tractus solitarius). The present results suggest that these encephalic areas and brainstem nuclei may be related to the development and/or maintenance of portal hypertension in this animal model.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0197-0186
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10355484-Animals,
pubmed-meshheading:10355484-Homeostasis,
pubmed-meshheading:10355484-Hypertension, Portal,
pubmed-meshheading:10355484-Male,
pubmed-meshheading:10355484-Norepinephrine,
pubmed-meshheading:10355484-Pons,
pubmed-meshheading:10355484-Portal Pressure,
pubmed-meshheading:10355484-Rats,
pubmed-meshheading:10355484-Rats, Wistar
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pubmed:year |
1999
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pubmed:articleTitle |
Norepinephrine uptake modifications in circumventricular organs, pons and myelencephalic areas and nuclei in prehepatic portal hypertensive rats.
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pubmed:affiliation |
Cátedras de Fisiopatología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina. mvatta@ffyb.uba.ar
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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