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pubmed-article:10348819pubmed:abstractTextWe have previously shown that autocrine insulin-like growth factor (IGF)-II synthesis through IGF-I receptor stimulates proliferation and inhibits differentiation of Caco-2 cells. To demonstrate whether differentiation of Caco-2 cells is dependent on cell growth status, we analyzed the effect of cell cycle arrest on differentiation of wild-type and IGF-II-overexpressing cells.lld:pubmed
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pubmed-article:10348819pubmed:articleTitleCell cycle block at G1-S or G2-M phase correlates with differentiation of Caco-2 cells: effect of constitutive insulin-like growth factor II expression.lld:pubmed
pubmed-article:10348819pubmed:affiliationCentro di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche "G. Salvatore," Dipartimento di Biologia e Patologia Cellulare e Molecolare "L. Califano, Naples, Italy.lld:pubmed
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