Linked Life Data

10323066

Source:http://linkedlifedata.com/resource/pubmed/id/10323066

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1999-5-19
pubmed:abstractText
Author is first discussing sepsis and its new categories (SIRS, MODS), its pathogenesis and symptoms. One axis of the events is the release of inflammatory and anti-inflammatory cytokines from the monocytes and macrophages, due to the precipitating injury. The other one is the activation of the polymorphonuclear leucocytes and the endothelial cells and their interaction. The basically non infectious SIRS is often maintained and worsened to MODS by the "translocation" of bacteria and endotoxins from the gut into the circulation. It is a new development the use of the serum procalcitonin level for the diagnosis, differential-diagnosis and for the evaluation of the success of the therapy. The causal therapy of the sepsis is still the surgical management of the septic focus, which should be supported by antibiotics and non-specific treatment (fluid-load, ventilation, inotropic, vasoactive and immunogenic drugs). It is new knowledge the effect of antibiotics on the immuno-system. For the treatment of SIRS, it has been tried many anti-cytokine and immunomodulating therapy; author explains the presumable causes of the failure of their majority.
pubmed:commentsCorrections
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0030-6002
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
140
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
515-20
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Latest results of intensive care of sepsis, septic shock and multiple organ injuries].
pubmed:affiliation
Aneszteziológiai és Intenzív Betegellátó Osztálya, Szent Rókus Kórház és Intézményei, Budapest.
pubmed:publicationType
Journal Article, English Abstract, Review