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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1999-4-29
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pubmed:abstractText |
Primary sclerosing cholangitis is associated with the HLA haplotypes A1-B8-DRB3*0101-DRB1*0301-DQA1*0501-DQB1*0201 and DRB3*0101-DRB1*1301-DQA1*0103-DQB1* 0603. However, the interpretation of these genetic associations is controversial. One explanation may be that HLA-encoded susceptibility is due to other genes carried on these haplotypes such as the HLA class III tumor necrosis factor genes. The aim of the study was to investigate tumor necrosis factor genetics in a large series of well-defined patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
237-41
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10068102-Adult,
pubmed-meshheading:10068102-Alleles,
pubmed-meshheading:10068102-Cholangitis, Sclerosing,
pubmed-meshheading:10068102-Female,
pubmed-meshheading:10068102-HLA-A1 Antigen,
pubmed-meshheading:10068102-HLA-B8 Antigen,
pubmed-meshheading:10068102-HLA-DR Antigens,
pubmed-meshheading:10068102-HLA-DRB1 Chains,
pubmed-meshheading:10068102-Humans,
pubmed-meshheading:10068102-Male,
pubmed-meshheading:10068102-Polymorphism, Genetic,
pubmed-meshheading:10068102-Tumor Necrosis Factor-alpha
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pubmed:year |
1999
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pubmed:articleTitle |
Association of tumor necrosis factor polymorphism with primary sclerosing cholangitis.
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pubmed:affiliation |
Institute of Liver Studies, King's College Hospital and King's College School of Medicine and Dentistry, London, UK.
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pubmed:publicationType |
Journal Article
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