|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1999-4-21
|
|
pubmed:abstractText |
Histamine is the most important chemical mediator in the pathogenesis of nasal allergy. Diesel exhaust particulates (DEPs) are common air pollutants from diesel engine-powered car exhaust and cause chronic airway diseases. Recently we observed that the nasal reactivity to histamine was enhanced in diesel exhaust-exposed guinea-pigs. It was also revealed that epithelial cells and endothelial cells in the airway produce certain cytokines in response to histamine.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0954-7894
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
52-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10051702-Cell Survival,
pubmed-meshheading:10051702-Endothelium, Vascular,
pubmed-meshheading:10051702-Epithelial Cells,
pubmed-meshheading:10051702-Gene Expression,
pubmed-meshheading:10051702-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:10051702-Histamine,
pubmed-meshheading:10051702-Humans,
pubmed-meshheading:10051702-Interleukin-8,
pubmed-meshheading:10051702-Nasal Mucosa,
pubmed-meshheading:10051702-RNA, Messenger,
pubmed-meshheading:10051702-Receptors, Histamine,
pubmed-meshheading:10051702-Time Factors,
pubmed-meshheading:10051702-Up-Regulation,
pubmed-meshheading:10051702-Vehicle Emissions
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Diesel exhaust particulates upregulate histamine receptor mRNA and increase histamine-induced IL-8 and GM-CSF production in nasal epithelial cells and endothelial cells.
|
|
pubmed:affiliation |
Department of Otorhinolaryngology, Chiba University, School of Medicine, Chiba City, Japan.
|
|
pubmed:publicationType |
Journal Article
|
