Linked Life Data

CPATH-87486

Source:http://cbio.mskcc.org/cpath#CPATH-87486

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-87486rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...cpath:CPATH-LOCAL-359172lld:biogrid
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cpath:CPATH-87486http://www.biopax.org/relea...cpath:CPATH-LOCAL-359181lld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...cpath:CPATH-LOCAL-368115lld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...SH2 domain-containing protein 3Clld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...SH2D3_HUMANlld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...cpath:CPATH-LOCAL-359182lld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...Novel SH2-containing protein 3lld:biogrid
cpath:CPATH-87486http://www.biopax.org/relea...FUNCTION: Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity). SUBUNIT: Interacts with PTK2B. Isoform 2 interacts with BCAR1/CAS and NEDD9/HEF1 (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity). Note=Associated with the membrane when EGF-stimulated. Found at ruffling membranes (By similarity). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8N5H7-1; Sequence=Displayed; Name=2; IsoId=Q8N5H7-2; Sequence=VSP_017707; Name=3; IsoId=Q8N5H7-3; Sequence=VSP_017706; Note=No experimental confirmation available; Name=4; IsoId=Q8N5H7-4; Sequence=VSP_017708; Note=No experimental confirmation available; TISSUE SPECIFICITY: Ubiquitously expressed. SIMILARITY: Contains 1 Ras-GEF domain. SIMILARITY: Contains 1 SH2 domain. SEQUENCE CAUTION: Sequence=AAQ88456.1; Type=Erroneous initiation; GENE SYNONYMS: NSP3. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-87486skos:exactMatchuniprot-protein:Q8N5H7lld:mappings
cpath:CPATH-LOCAL-10999360http://www.biopax.org/relea...cpath:CPATH-87486lld:biogrid
cpath:CPATH-LOCAL-11052159http://www.biopax.org/relea...cpath:CPATH-87486lld:biogrid
cpath:CPATH-LOCAL-11297725http://www.biopax.org/relea...cpath:CPATH-87486lld:biogrid
cpath:CPATH-LOCAL-11564649http://www.biopax.org/relea...cpath:CPATH-87486lld:biogrid