Linked Life Data

CPATH-83698

Source:http://cbio.mskcc.org/cpath#CPATH-83698

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-83698rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345280lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345281lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345282lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345283lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345284lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-351345lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...Thrombospondin-2lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...TSP2_MOUSElld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...cpath:CPATH-LOCAL-345285lld:biogrid
cpath:CPATH-83698http://www.biopax.org/relea...FUNCTION: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. SUBUNIT: Homotrimer; disulfide-linked. Can bind to fibrinogen, fibronectin, laminin and type V collagen (By similarity). Interacts (via the TSP type I repeats) with CD36; the interaction conveys an antiangiogenic effect. Interacts (via the TSP type I repeats) with HRG; the interaction blocks the antiangiogenic effect of THBS2 with CD36. Can bind to fibrinogen, fibronectin, laminin. SIMILARITY: Belongs to the thrombospondin family. SIMILARITY: Contains 3 EGF-like domains. SIMILARITY: Contains 1 TSP C-terminal (TSPC) domain. SIMILARITY: Contains 1 TSP N-terminal (TSPN) domain. SIMILARITY: Contains 3 TSP type-1 domains. SIMILARITY: Contains 8 TSP type-3 repeats. SIMILARITY: Contains 1 VWFC domain. GENE SYNONYMS: Tsp2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-83698skos:exactMatchuniprot-protein:Q03350lld:mappings
cpath:CPATH-83698skos:closeMatchentrez-gene:21826lld:mappings
cpath:CPATH-LOCAL-10477270http://www.biopax.org/relea...cpath:CPATH-83698lld:biogrid
cpath:CPATH-LOCAL-10477271http://www.biopax.org/relea...cpath:CPATH-83698lld:biogrid
cpath:CPATH-LOCAL-10496215http://www.biopax.org/relea...cpath:CPATH-83698lld:biogrid
cpath:CPATH-LOCAL-10509895http://www.biopax.org/relea...cpath:CPATH-83698lld:biogrid