| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-232330,
cpath:CPATH-LOCAL-232330,
cpath:CPATH-LOCAL-232331,
cpath:CPATH-LOCAL-232331,
cpath:CPATH-LOCAL-232332,
cpath:CPATH-LOCAL-232332,
cpath:CPATH-LOCAL-232333,
cpath:CPATH-LOCAL-232333,
cpath:CPATH-LOCAL-232334,
cpath:CPATH-LOCAL-232334,
cpath:CPATH-LOCAL-232335,
cpath:CPATH-LOCAL-232335,
cpath:CPATH-LOCAL-241735,
cpath:CPATH-LOCAL-241735
|
| http://www.biopax.org/relea... |
Serine/threonine-protein kinase N2,
Serine/threonine-protein kinase N2
|
| http://www.biopax.org/relea... |
PKN2_HUMAN,
PKN2_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.7.11.13,
2.7.11.13,
Protein kinase C-like 2,
Protein kinase C-like 2,
Protein-kinase C-related kinase 2,
Protein-kinase C-related kinase 2
|
| http://www.biopax.org/relea... |
FUNCTION: Exhibits a preference for highly basic protein substrates (By similarity). CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. ENZYME REGULATION: Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). DOMAIN: The C1 domain does not bind the diacylglycerol (DAG). PTM: Autophosphorylated. PTM: Activated by limited proteolysis with trypsin (By similarity). SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. SIMILARITY: Contains 1 AGC-kinase C-terminal domain. SIMILARITY: Contains 1 C2 domain. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 3 REM (Hr1) repeats. GENE SYNONYMS: PRK2 PRKCL2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Exhibits a preference for highly basic protein substrates (By similarity). CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. ENZYME REGULATION: Activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids. Two specific sites, Thr-816 (activation loop of the kinase domain) and Thr-958 (turn motif), need to be phosphorylated for its full activation (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). DOMAIN: The C1 domain does not bind the diacylglycerol (DAG). PTM: Autophosphorylated. PTM: Activated by limited proteolysis with trypsin (By similarity). SIMILARITY: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. SIMILARITY: Contains 1 AGC-kinase C-terminal domain. SIMILARITY: Contains 1 C2 domain. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 3 REM (Hr1) repeats. GENE SYNONYMS: PRK2 PRKCL2. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |