Linked Life Data

CPATH-49737

Source:http://cbio.mskcc.org/cpath#CPATH-49737

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-49737rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-49737rdf:typehttp://www.biopax.org/relea...lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199551lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199551lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199552lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199552lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199553lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199553lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199554lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199554lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199555lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199555lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199556lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199556lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199557lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199557lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199558lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199558lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-206191lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-206191lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptorlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptorlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...RON_HUMANlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...RON_HUMANlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199549lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...cpath:CPATH-LOCAL-199549lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...2.7.10.1lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...2.7.10.1lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptor beta chainlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptor beta chainlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...p185-Ronlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...p185-Ronlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...Protein-tyrosine kinase 8lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...Protein-tyrosine kinase 8lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...CDw136lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...CDw136lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...MSP receptorlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...MSP receptorlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptor alpha chainlld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...Macrophage-stimulating protein receptor alpha chainlld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...CD136lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...CD136lld:cellmap
cpath:CPATH-49737http://www.biopax.org/relea...FUNCTION: Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=6; Name=RON; IsoId=Q04912-1; Sequence=Displayed; Name=Delta-RON; IsoId=Q04912-2; Sequence=VSP_005007; Note=Lacks part of the extracellular domain, oligomerizes and is constitutively activated; Name=RON-1; IsoId=Q04912-3; Sequence=VSP_038920, VSP_038921; Name=RON-2; IsoId=Q04912-4; Sequence=VSP_038919, VSP_038922, VSP_038923; Name=RON-3; IsoId=Q04912-5; Sequence=VSP_038924, VSP_038925; Name=RON-4; IsoId=Q04912-6; Sequence=VSP_038922, VSP_038923; TISSUE SPECIFICITY: Keratinocytes and lung. PTM: Proteolytic processing yields the two subunits. PTM: Phosphorylated in response to ligand binding (Probable). SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SIMILARITY: Contains 3 IPT/TIG domains. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 1 Sema domain. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RONID287.html"; GENE SYNONYMS: PTK8 RON. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-49737http://www.biopax.org/relea...FUNCTION: Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=6; Name=RON; IsoId=Q04912-1; Sequence=Displayed; Name=Delta-RON; IsoId=Q04912-2; Sequence=VSP_005007; Note=Lacks part of the extracellular domain, oligomerizes and is constitutively activated; Name=RON-1; IsoId=Q04912-3; Sequence=VSP_038920, VSP_038921; Name=RON-2; IsoId=Q04912-4; Sequence=VSP_038919, VSP_038922, VSP_038923; Name=RON-3; IsoId=Q04912-5; Sequence=VSP_038924, VSP_038925; Name=RON-4; IsoId=Q04912-6; Sequence=VSP_038922, VSP_038923; TISSUE SPECIFICITY: Keratinocytes and lung. PTM: Proteolytic processing yields the two subunits. PTM: Phosphorylated in response to ligand binding (Probable). SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SIMILARITY: Contains 3 IPT/TIG domains. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 1 Sema domain. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RONID287.html"; GENE SYNONYMS: PTK8 RON. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:cellmap
cpath:CPATH-49737skos:exactMatchuniprot-protein:Q04912lld:mappings
cpath:CPATH-49737skos:closeMatchentrez-gene:4486lld:mappings
cpath:CPATH-LOCAL-11055010http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11151190http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11189244http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11212029http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11230045http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11249170http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11310609http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11602780http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11698735http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11724445http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11762184http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-11846140http://www.biopax.org/relea...cpath:CPATH-49737lld:biogrid
cpath:CPATH-LOCAL-7757135http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757165http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757169http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757365http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757626http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757728http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7757940http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap
cpath:CPATH-LOCAL-7758032http://www.biopax.org/relea...cpath:CPATH-49737lld:cellmap