| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-199551,
cpath:CPATH-LOCAL-199551,
cpath:CPATH-LOCAL-199552,
cpath:CPATH-LOCAL-199552,
cpath:CPATH-LOCAL-199553,
cpath:CPATH-LOCAL-199553,
cpath:CPATH-LOCAL-199554,
cpath:CPATH-LOCAL-199554,
cpath:CPATH-LOCAL-199555,
cpath:CPATH-LOCAL-199555,
cpath:CPATH-LOCAL-199556,
cpath:CPATH-LOCAL-199556,
cpath:CPATH-LOCAL-199557,
cpath:CPATH-LOCAL-199557,
cpath:CPATH-LOCAL-199558,
cpath:CPATH-LOCAL-199558,
cpath:CPATH-LOCAL-206191,
cpath:CPATH-LOCAL-206191
|
| http://www.biopax.org/relea... |
Macrophage-stimulating protein receptor,
Macrophage-stimulating protein receptor
|
| http://www.biopax.org/relea... |
RON_HUMAN,
RON_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
2.7.10.1,
2.7.10.1,
CD136,
CD136,
CDw136,
CDw136,
MSP receptor,
MSP receptor,
Macrophage-stimulating protein receptor alpha chain,
Macrophage-stimulating protein receptor alpha chain,
Macrophage-stimulating protein receptor beta chain,
Macrophage-stimulating protein receptor beta chain,
Protein-tyrosine kinase 8,
Protein-tyrosine kinase 8,
p185-Ron,
p185-Ron
|
| http://www.biopax.org/relea... |
FUNCTION: Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=6; Name=RON; IsoId=Q04912-1; Sequence=Displayed; Name=Delta-RON; IsoId=Q04912-2; Sequence=VSP_005007; Note=Lacks part of the extracellular domain, oligomerizes and is constitutively activated; Name=RON-1; IsoId=Q04912-3; Sequence=VSP_038920, VSP_038921; Name=RON-2; IsoId=Q04912-4; Sequence=VSP_038919, VSP_038922, VSP_038923; Name=RON-3; IsoId=Q04912-5; Sequence=VSP_038924, VSP_038925; Name=RON-4; IsoId=Q04912-6; Sequence=VSP_038922, VSP_038923; TISSUE SPECIFICITY: Keratinocytes and lung. PTM: Proteolytic processing yields the two subunits. PTM: Phosphorylated in response to ligand binding (Probable). SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SIMILARITY: Contains 3 IPT/TIG domains. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 1 Sema domain. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RONID287.html"; GENE SYNONYMS: PTK8 RON. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. CATALYTIC ACTIVITY: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=6; Name=RON; IsoId=Q04912-1; Sequence=Displayed; Name=Delta-RON; IsoId=Q04912-2; Sequence=VSP_005007; Note=Lacks part of the extracellular domain, oligomerizes and is constitutively activated; Name=RON-1; IsoId=Q04912-3; Sequence=VSP_038920, VSP_038921; Name=RON-2; IsoId=Q04912-4; Sequence=VSP_038919, VSP_038922, VSP_038923; Name=RON-3; IsoId=Q04912-5; Sequence=VSP_038924, VSP_038925; Name=RON-4; IsoId=Q04912-6; Sequence=VSP_038922, VSP_038923; TISSUE SPECIFICITY: Keratinocytes and lung. PTM: Proteolytic processing yields the two subunits. PTM: Phosphorylated in response to ligand binding (Probable). SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SIMILARITY: Contains 3 IPT/TIG domains. SIMILARITY: Contains 1 protein kinase domain. SIMILARITY: Contains 1 Sema domain. WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/RONID287.html"; GENE SYNONYMS: PTK8 RON. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |