cpath:CPATH-444 | rdf:type | http://www.biopax.org/relea... | lld:biogrid |
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cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2029 | lld:cellmap |
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cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2030 | lld:cellmap |
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cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2033 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2034 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2034 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2035 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2035 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2036 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2036 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2037 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2037 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2038 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2038 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2039 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2039 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-9357 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-9357 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | Cell division cycle protein 23 homolog | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | Cell division cycle protein 23 homolog | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | CDC23_HUMAN | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | CDC23_HUMAN | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2027 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-2027 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | Cyclosome subunit 8 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | Cyclosome subunit 8 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | APC8 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | APC8 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | Anaphase-promoting complex subunit 8 | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | Anaphase-promoting complex subunit 8 | lld:cellmap |
cpath:CPATH-444 | http://www.biopax.org/relea... | FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: The APC/C is composed of at least 12 subunits. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9UJX2-1; Sequence=Displayed; Name=2; IsoId=Q9UJX2-2; Sequence=VSP_008429, VSP_008430; Note=No experimental confirmation available; Name=3; IsoId=Q9UJX2-3; Sequence=VSP_037678; Note=No experimental confirmation available; PTM: Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis. SIMILARITY: Belongs to the APC8/CDC23 family. SIMILARITY: Contains 9 TPR repeats. SEQUENCE CAUTION: Sequence=AAC70920.1; Type=Erroneous initiation; Sequence=AAH05258.1; Type=Erroneous initiation; Sequence=AAH10944.1; Type=Erroneous initiation; Sequence=AAH17713.1; Type=Erroneous initiation; Sequence=AAS99353.1; Type=Erroneous initiation; Sequence=BAA75628.1; Type=Erroneous initiation; Sequence=BAD96970.1; Type=Erroneous initiation; Sequence=BAF84299.1; Type=Erroneous initiation; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdc23/"; GENE SYNONYMS: ANAPC8. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License. | lld:biogrid |
cpath:CPATH-444 | http://www.biopax.org/relea... | FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: The APC/C is composed of at least 12 subunits. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q9UJX2-1; Sequence=Displayed; Name=2; IsoId=Q9UJX2-2; Sequence=VSP_008429, VSP_008430; Note=No experimental confirmation available; Name=3; IsoId=Q9UJX2-3; Sequence=VSP_037678; Note=No experimental confirmation available; PTM: Phosphorylated. Phosphorylation on Thr-562 occurs specifically during mitosis. SIMILARITY: Belongs to the APC8/CDC23 family. SIMILARITY: Contains 9 TPR repeats. SEQUENCE CAUTION: Sequence=AAC70920.1; Type=Erroneous initiation; Sequence=AAH05258.1; Type=Erroneous initiation; Sequence=AAH10944.1; Type=Erroneous initiation; Sequence=AAH17713.1; Type=Erroneous initiation; Sequence=AAS99353.1; Type=Erroneous initiation; Sequence=BAA75628.1; Type=Erroneous initiation; Sequence=BAD96970.1; Type=Erroneous initiation; Sequence=BAF84299.1; Type=Erroneous initiation; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdc23/"; GENE SYNONYMS: ANAPC8. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License. | lld:cellmap |
cpath:CPATH-444 | skos:exactMatch | uniprot-protein:Q9UJX2 | lld:mappings |
cpath:CPATH-444 | skos:closeMatch | entrez-gene:8697 | lld:mappings |
cpath:CPATH-LOCAL-11007549 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11042244 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11097475 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11099095 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11108500 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11127535 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11141739 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11594304 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11611104 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-11788119 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
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cpath:CPATH-LOCAL-11892384 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:biogrid |
cpath:CPATH-LOCAL-7770835 | http://www.biopax.org/relea... | cpath:CPATH-444 | lld:cellmap |
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