Linked Life Data

CPATH-374

Source:http://cbio.mskcc.org/cpath#CPATH-374

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-374rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1727lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1728lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1729lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1730lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1731lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-9322lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...Ceramide synthase 1lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...CERS1_HUMANlld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...cpath:CPATH-LOCAL-1725lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...CerS1lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...Protein UOG-1lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...Longevity assurance gene 1 protein homolog 1lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...LAG1 longevity assurance homolog 1lld:biogrid
cpath:CPATH-374http://www.biopax.org/relea...FUNCTION: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity). SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). SUBCELLULAR LOCATION: Isoform 1: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Golgi apparatus membrane; Multi-pass membrane protein (By similarity). Note=Isoform 1 may recycle from the Golgi to the endoplasmic reticulum. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=P27544-1; Sequence=Displayed; Name=2; IsoId=P27544-2; Sequence=VSP_003049; Note=No experimental confirmation available; MISCELLANEOUS: This protein is produced by a bicistronic gene which also produces the GDF1 protein from a non-overlapping reading frame. SIMILARITY: Contains 1 TLC (TRAM/LAG1/CLN8) domain. GENE SYNONYMS: LAG1 LASS1 UOG1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-374skos:exactMatchuniprot-protein:P27544lld:mappings
cpath:CPATH-374skos:closeMatchentrez-gene:10715lld:mappings
cpath:CPATH-LOCAL-11710479http://www.biopax.org/relea...cpath:CPATH-374lld:biogrid