Linked Life Data

CPATH-350

Source:http://cbio.mskcc.org/cpath#CPATH-350

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-350rdf:typehttp://www.biopax.org/relea...lld:biogrid
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cpath:CPATH-350http://www.biopax.org/relea...cpath:CPATH-LOCAL-1629lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...cpath:CPATH-LOCAL-9310lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...Natural killer cell receptor 2B4lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...CD244_HUMANlld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...cpath:CPATH-LOCAL-1615lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...NKR2B4lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...CD244lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...NK cell type I receptor protein 2B4lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...NAILlld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...NK cell activation-inducing ligandlld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...h2B4lld:biogrid
cpath:CPATH-350http://www.biopax.org/relea...FUNCTION: Modulate other receptor-ligand interactions to enhance leukocyte activation. SUBUNIT: Interacts with CD48. Following phosphorylation, it is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. Binding of SH2D1A/SAP to CD244 prevents its association with PTPN11/SHP-2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=4; Name=1; Synonyms=H2B4-B; IsoId=Q9BZW8-1; Sequence=Displayed; Note=No experimental confirmation available; Name=2; Synonyms=H2B4-A; IsoId=Q9BZW8-2; Sequence=VSP_010397; Name=3; Synonyms=H2B4; IsoId=Q9BZW8-3; Sequence=VSP_010397, VSP_010399, VSP_010400; Note=No experimental confirmation available; Name=4; Synonyms=H2B4b; IsoId=Q9BZW8-4; Sequence=VSP_010398; Note=No experimental confirmation available; TISSUE SPECIFICITY: Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. SIMILARITY: Contains 2 Ig-like (immunoglobulin-like) domains. GENE SYNONYMS: 2B4. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-350skos:exactMatchuniprot-protein:Q9BZW8lld:mappings
cpath:CPATH-350skos:closeMatchentrez-gene:51744lld:mappings
cpath:CPATH-LOCAL-11085205http://www.biopax.org/relea...cpath:CPATH-350lld:biogrid