| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-1617,
cpath:CPATH-LOCAL-1618,
cpath:CPATH-LOCAL-1619,
cpath:CPATH-LOCAL-1620,
cpath:CPATH-LOCAL-1621,
cpath:CPATH-LOCAL-1622,
cpath:CPATH-LOCAL-1623,
cpath:CPATH-LOCAL-1624,
cpath:CPATH-LOCAL-1625,
cpath:CPATH-LOCAL-1626,
cpath:CPATH-LOCAL-1627,
cpath:CPATH-LOCAL-1628,
cpath:CPATH-LOCAL-1629,
cpath:CPATH-LOCAL-9310
|
| http://www.biopax.org/relea... |
Natural killer cell receptor 2B4
|
| http://www.biopax.org/relea... |
CD244_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD244,
NAIL,
NK cell activation-inducing ligand,
NK cell type I receptor protein 2B4,
NKR2B4,
h2B4
|
| http://www.biopax.org/relea... |
FUNCTION: Modulate other receptor-ligand interactions to enhance leukocyte activation. SUBUNIT: Interacts with CD48. Following phosphorylation, it is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. Binding of SH2D1A/SAP to CD244 prevents its association with PTPN11/SHP-2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential). ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=4; Name=1; Synonyms=H2B4-B; IsoId=Q9BZW8-1; Sequence=Displayed; Note=No experimental confirmation available; Name=2; Synonyms=H2B4-A; IsoId=Q9BZW8-2; Sequence=VSP_010397; Name=3; Synonyms=H2B4; IsoId=Q9BZW8-3; Sequence=VSP_010397, VSP_010399, VSP_010400; Note=No experimental confirmation available; Name=4; Synonyms=H2B4b; IsoId=Q9BZW8-4; Sequence=VSP_010398; Note=No experimental confirmation available; TISSUE SPECIFICITY: Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils. SIMILARITY: Contains 2 Ig-like (immunoglobulin-like) domains. GENE SYNONYMS: 2B4. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:exactMatch | |
| skos:closeMatch |