Linked Life Data

CPATH-32877

Source:http://cbio.mskcc.org/cpath#CPATH-32877

Statements in which the resource exists.
SubjectPredicateObjectContext
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cpath:CPATH-32877http://www.biopax.org/relea...cpath:CPATH-LOCAL-139281lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...Probable ATP-dependent RNA helicase DDX6lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...DDX6_HUMANlld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...cpath:CPATH-LOCAL-134440lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...3.6.4.13lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...ATP-dependent RNA helicase p54lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...Oncogene RCKlld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...DEAD box protein 6lld:biogrid
cpath:CPATH-32877http://www.biopax.org/relea...FUNCTION: In the process of mRNA degradation, may play a role in mRNA decapping. CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate. SUBUNIT: Forms a complex with DCP1A, DCP2, EDC3 and EDC4/HEDLS. SUBCELLULAR LOCATION: Cytoplasm, P-body. Note=Processing bodies (PB). TISSUE SPECIFICITY: Abundantly expressed in most tissues. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Note=A chromosomal aberration involving DDX6 may be a cause of hematopoietic tumors such as B-cell lymphomas. Translocation t(11;14)(q23;q32). SIMILARITY: Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily. SIMILARITY: Contains 1 helicase ATP-binding domain. SIMILARITY: Contains 1 helicase C-terminal domain. GENE SYNONYMS: HLR2 RCK. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
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cpath:CPATH-32877skos:closeMatchentrez-gene:1656lld:mappings
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cpath:CPATH-LOCAL-11816214http://www.biopax.org/relea...cpath:CPATH-32877lld:biogrid
cpath:CPATH-LOCAL-11917269http://www.biopax.org/relea...cpath:CPATH-32877lld:biogrid