cpath:CPATH-276 | rdf:type | http://www.biopax.org/relea... | lld:biogrid |
cpath:CPATH-276 | rdf:type | http://www.biopax.org/relea... | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1288 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1288 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1289 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1289 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1290 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1290 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1291 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1291 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1292 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1292 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1293 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1293 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1294 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1294 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1295 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1295 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1296 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1296 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-9273 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-9273 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain-1 catalytic subunit | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain-1 catalytic subunit | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | CAN1_HUMAN | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | CAN1_HUMAN | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1286 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | cpath:CPATH-LOCAL-1286 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Micromolar-calpain | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Micromolar-calpain | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain mu-type | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain mu-type | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | muCANP | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | muCANP | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Cell proliferation-inducing gene 30 protein | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Cell proliferation-inducing gene 30 protein | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | CANP 1 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | CANP 1 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calcium-activated neutral proteinase 1 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calcium-activated neutral proteinase 1 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain-1 large subunit | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | Calpain-1 large subunit | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | 3.4.22.52 | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | 3.4.22.52 | lld:imid |
cpath:CPATH-276 | http://www.biopax.org/relea... | FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. CATALYTIC ACTIVITY: Broad endopeptidase specificity. COFACTOR: Binds 3 calcium ions. ENZYME REGULATION: Activated by micromolar concentrations of calcium and inhibited by calpastatin. SUBUNIT: Forms a heterodimer with a small (regulatory) subunit (CAPNS1). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocates to the plasma membrane upon Ca(2+) binding (By similarity). TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the peptidase C2 family. SIMILARITY: Contains 1 calpain catalytic domain. SIMILARITY: Contains 4 EF-hand domains. WEB RESOURCE: Name=CaBP; Note=Calpain; URL="http://structbio.vanderbilt.edu/cabp_database/general/prot_pages/calpain.html"; WEB RESOURCE: Name=Calpains homepage; URL="http://ag.arizona.edu/calpains/"; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/capn1/"; GENE SYNONYMS: CANPL1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License. | lld:biogrid |
cpath:CPATH-276 | http://www.biopax.org/relea... | FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. CATALYTIC ACTIVITY: Broad endopeptidase specificity. COFACTOR: Binds 3 calcium ions. ENZYME REGULATION: Activated by micromolar concentrations of calcium and inhibited by calpastatin. SUBUNIT: Forms a heterodimer with a small (regulatory) subunit (CAPNS1). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocates to the plasma membrane upon Ca(2+) binding (By similarity). TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the peptidase C2 family. SIMILARITY: Contains 1 calpain catalytic domain. SIMILARITY: Contains 4 EF-hand domains. WEB RESOURCE: Name=CaBP; Note=Calpain; URL="http://structbio.vanderbilt.edu/cabp_database/general/prot_pages/calpain.html"; WEB RESOURCE: Name=Calpains homepage; URL="http://ag.arizona.edu/calpains/"; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/capn1/"; GENE SYNONYMS: CANPL1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License. | lld:imid |
cpath:CPATH-276 | skos:exactMatch | uniprot-protein:P07384 | lld:mappings |
cpath:CPATH-276 | skos:closeMatch | entrez-gene:823 | lld:mappings |
cpath:CPATH-LOCAL-10945464 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11078424 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11121625 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11213665 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11260779 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11283864 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11299105 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11364955 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11524989 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11616850 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11701225 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11836944 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-11876935 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:biogrid |
cpath:CPATH-LOCAL-7784459 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |
cpath:CPATH-LOCAL-7785731 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |
cpath:CPATH-LOCAL-7786021 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |
cpath:CPATH-LOCAL-7786079 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |
cpath:CPATH-LOCAL-7786762 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |
cpath:CPATH-LOCAL-7787407 | http://www.biopax.org/relea... | cpath:CPATH-276 | lld:imid |