| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-1288,
cpath:CPATH-LOCAL-1288,
cpath:CPATH-LOCAL-1289,
cpath:CPATH-LOCAL-1289,
cpath:CPATH-LOCAL-1290,
cpath:CPATH-LOCAL-1290,
cpath:CPATH-LOCAL-1291,
cpath:CPATH-LOCAL-1291,
cpath:CPATH-LOCAL-1292,
cpath:CPATH-LOCAL-1292,
cpath:CPATH-LOCAL-1293,
cpath:CPATH-LOCAL-1293,
cpath:CPATH-LOCAL-1294,
cpath:CPATH-LOCAL-1294,
cpath:CPATH-LOCAL-1295,
cpath:CPATH-LOCAL-1295,
cpath:CPATH-LOCAL-1296,
cpath:CPATH-LOCAL-1296,
cpath:CPATH-LOCAL-9273,
cpath:CPATH-LOCAL-9273
|
| http://www.biopax.org/relea... |
Calpain-1 catalytic subunit,
Calpain-1 catalytic subunit
|
| http://www.biopax.org/relea... |
CAN1_HUMAN,
CAN1_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
3.4.22.52,
3.4.22.52,
CANP 1,
CANP 1,
Calcium-activated neutral proteinase 1,
Calcium-activated neutral proteinase 1,
Calpain mu-type,
Calpain mu-type,
Calpain-1 large subunit,
Calpain-1 large subunit,
Cell proliferation-inducing gene 30 protein,
Cell proliferation-inducing gene 30 protein,
Micromolar-calpain,
Micromolar-calpain,
muCANP,
muCANP
|
| http://www.biopax.org/relea... |
FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. CATALYTIC ACTIVITY: Broad endopeptidase specificity. COFACTOR: Binds 3 calcium ions. ENZYME REGULATION: Activated by micromolar concentrations of calcium and inhibited by calpastatin. SUBUNIT: Forms a heterodimer with a small (regulatory) subunit (CAPNS1). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocates to the plasma membrane upon Ca(2+) binding (By similarity). TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the peptidase C2 family. SIMILARITY: Contains 1 calpain catalytic domain. SIMILARITY: Contains 4 EF-hand domains. WEB RESOURCE: Name=CaBP; Note=Calpain; URL="http://structbio.vanderbilt.edu/cabp_database/general/prot_pages/calpain.html"; WEB RESOURCE: Name=Calpains homepage; URL="http://ag.arizona.edu/calpains/"; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/capn1/"; GENE SYNONYMS: CANPL1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. CATALYTIC ACTIVITY: Broad endopeptidase specificity. COFACTOR: Binds 3 calcium ions. ENZYME REGULATION: Activated by micromolar concentrations of calcium and inhibited by calpastatin. SUBUNIT: Forms a heterodimer with a small (regulatory) subunit (CAPNS1). SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell membrane (By similarity). Note=Translocates to the plasma membrane upon Ca(2+) binding (By similarity). TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to the peptidase C2 family. SIMILARITY: Contains 1 calpain catalytic domain. SIMILARITY: Contains 4 EF-hand domains. WEB RESOURCE: Name=CaBP; Note=Calpain; URL="http://structbio.vanderbilt.edu/cabp_database/general/prot_pages/calpain.html"; WEB RESOURCE: Name=Calpains homepage; URL="http://ag.arizona.edu/calpains/"; WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/capn1/"; GENE SYNONYMS: CANPL1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |