Linked Life Data

CPATH-174

Source:http://cbio.mskcc.org/cpath#CPATH-174

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-174rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-805lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-806lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-807lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-808lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-809lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-810lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-9222lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...CD180 antigenlld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...CD180_HUMANlld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...cpath:CPATH-LOCAL-803lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...Lymphocyte antigen 64lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...Radioprotective 105 kDa proteinlld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...CD180lld:biogrid
cpath:CPATH-174http://www.biopax.org/relea...FUNCTION: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). SUBUNIT: Binds to MD-1. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. SIMILARITY: Belongs to the Toll-like receptor family. SIMILARITY: Contains 19 LRR (leucine-rich) repeats. SIMILARITY: Contains 1 LRRCT domain. GENE SYNONYMS: LY64 RP105. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-174skos:exactMatchuniprot-protein:Q99467lld:mappings
cpath:CPATH-174skos:closeMatchentrez-gene:4064lld:mappings
cpath:CPATH-LOCAL-11220835http://www.biopax.org/relea...cpath:CPATH-174lld:biogrid
cpath:CPATH-LOCAL-11796174http://www.biopax.org/relea...cpath:CPATH-174lld:biogrid