| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD180 antigen
|
| http://www.biopax.org/relea... |
CD180_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
CD180,
Lymphocyte antigen 64,
Radioprotective 105 kDa protein
|
| http://www.biopax.org/relea... |
FUNCTION: May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). SUBUNIT: Binds to MD-1. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. SIMILARITY: Belongs to the Toll-like receptor family. SIMILARITY: Contains 19 LRR (leucine-rich) repeats. SIMILARITY: Contains 1 LRRCT domain. GENE SYNONYMS: LY64 RP105. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
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| skos:closeMatch |