Linked Life Data

CPATH-149361

Source:http://cbio.mskcc.org/cpath#CPATH-149361

Statements in which the resource exists.
SubjectPredicateObjectContext
cpath:CPATH-149361rdf:typehttp://www.biopax.org/relea...lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617611lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617612lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617613lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617614lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617615lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617616lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617617lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617618lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-626585lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...High affinity immunoglobulin gamma Fc receptor Illd:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...FCGR1_HUMANlld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...cpath:CPATH-LOCAL-617609lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...IgG Fc receptor Illd:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...FcRIlld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...FcgammaRIalld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...CD64lld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...Fc-gamma RIlld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...Fc-gamma RIAlld:biogrid
cpath:CPATH-149361http://www.biopax.org/relea...FUNCTION: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. SUBUNIT: Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2, LAT and PPL. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Stabilized at the cell membrane through interaction with FCER1G. ALTERNATIVE PRODUCTS: Event=Alternative splicing; Named isoforms=2; Name=1; Synonyms=A; IsoId=P12314-1; Sequence=Displayed; Name=2; Synonyms=B; IsoId=P12314-2; Sequence=VSP_002637; TISSUE SPECIFICITY: Monocyte/macrophage specific. PTM: Phosphorylated on serine residues (By similarity). SIMILARITY: Belongs to the immunoglobulin superfamily. FCGR1 family. SIMILARITY: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. WEB RESOURCE: Name=FCGR1Abase; Note=FCGR1A mutation db; URL="http://bioinf.uta.fi/FCGR1Abase/"; GENE SYNONYMS: FCG1 FCGR1 IGFR1. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.lld:biogrid
cpath:CPATH-149361skos:exactMatchuniprot-protein:P12314lld:mappings
cpath:CPATH-149361skos:closeMatchentrez-gene:2209lld:mappings
cpath:CPATH-LOCAL-10954525http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid
cpath:CPATH-LOCAL-11060050http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid
cpath:CPATH-LOCAL-11082625http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid
cpath:CPATH-LOCAL-11514820http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid
cpath:CPATH-LOCAL-11574520http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid
cpath:CPATH-LOCAL-11785165http://www.biopax.org/relea...cpath:CPATH-149361lld:biogrid