| Predicate | Object |
|---|---|
| rdf:type | |
| http://www.biopax.org/relea... |
cpath:CPATH-LOCAL-4687,
cpath:CPATH-LOCAL-4687,
cpath:CPATH-LOCAL-4688,
cpath:CPATH-LOCAL-4688,
cpath:CPATH-LOCAL-4689,
cpath:CPATH-LOCAL-4689,
cpath:CPATH-LOCAL-4690,
cpath:CPATH-LOCAL-4690,
cpath:CPATH-LOCAL-4691,
cpath:CPATH-LOCAL-4691,
cpath:CPATH-LOCAL-4692,
cpath:CPATH-LOCAL-4692,
cpath:CPATH-LOCAL-4693,
cpath:CPATH-LOCAL-4693,
cpath:CPATH-LOCAL-9651,
cpath:CPATH-LOCAL-9651
|
| http://www.biopax.org/relea... |
Cell division cycle protein 27 homolog,
Cell division cycle protein 27 homolog
|
| http://www.biopax.org/relea... |
CDC27_HUMAN,
CDC27_HUMAN
|
| http://www.biopax.org/relea... | |
| http://www.biopax.org/relea... |
APC3,
APC3,
Anaphase-promoting complex subunit 3,
Anaphase-promoting complex subunit 3,
CDC27 homolog,
CDC27 homolog,
CDC27Hs,
CDC27Hs,
H-NUC,
H-NUC
|
| http://www.biopax.org/relea... |
FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: The APC/C is composed of at least 12 subunits. Interacts with RB. SUBCELLULAR LOCATION: Nucleus. PTM: Phosphorylated. Phosphorylation on Ser-426 and Thr-446 occurs specifically during mitosis. SIMILARITY: Belongs to the APC3/CDC27 family. SIMILARITY: Contains 9 TPR repeats. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdc27/"; GENE SYNONYMS: ANAPC3 D0S1430E D17S978E. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.,
FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. PATHWAY: Protein modification; protein ubiquitination. SUBUNIT: The APC/C is composed of at least 12 subunits. Interacts with RB. SUBCELLULAR LOCATION: Nucleus. PTM: Phosphorylated. Phosphorylation on Ser-426 and Thr-446 occurs specifically during mitosis. SIMILARITY: Belongs to the APC3/CDC27 family. SIMILARITY: Contains 9 TPR repeats. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/cdc27/"; GENE SYNONYMS: ANAPC3 D0S1430E D17S978E. COPYRIGHT: Protein annotation is derived from the UniProt Consortium (http://www.uniprot.org/). Distributed under the Creative Commons Attribution-NoDerivs License.
|
| skos:exactMatch | |
| skos:closeMatch |