Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:63622
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is sustituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias." []
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| skos:inScheme | |
| skos:prefLabel |
sotalol
|
| skos:altLabel |
N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide,
Sotalol
|
| skos:notation |
ChemIDplus:3930-20-9 "CAS Registry Number",
CiteXplore:20562595 "PubMed citation",
CiteXplore:21553267 "PubMed citation",
CiteXplore:21854895 "PubMed citation",
DrugBank:DB00489 "DrugBank",
KEGG COMPOUND:3930-20-9 "CAS Registry Number",
KEGG COMPOUND:C07309 "KEGG COMPOUND",
KEGG DRUG:D08525 "KEGG DRUG",
Reaxys:2380820 "Reaxys Registry Number",
Wikipedia:Sotalol "Wikipedia"
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| skos:broader | |
| skos:relatedSynonym |
sotalol,
4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide,
beta-cardone,
sotalolum,
C12H20N2O3S,
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1,
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3,
InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N
|