Source:http://linkedlifedata.com/resource/chebi/id/CHEBI:391960
| Predicate | Object |
|---|---|
| rdf:type | |
| skos:definition |
"2-[(3S)-1-Ethylpyrrolidin-3-yl]-2,2-diphenylacetamide in which one of the hydrogens at the 2-position of the ethyl group is substituted by a 2,3-dihydro-1-benzofuran-5-yl group. It is a selective antagonist for the M3 muscarinic acetylcholine receptor, which is primarily responsible for bladder muscle contractions, and is used as the hydrobromide salt in the management of urinary incontinence." []
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| skos:inScheme | |
| skos:prefLabel |
darifenacin
|
| skos:altLabel |
2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide,
DARIFENACIN
|
| skos:notation |
Beilstein:8449641 "Beilstein Registry Number",
ChEMBL:11831911 "PubMed citation",
ChemIDplus:133099-04-4 "CAS Registry Number",
CiteXplore:14616424 "PubMed citation",
DrugBank:DB00496 "DrugBank",
KEGG DRUG:D03654 "KEGG DRUG",
Wikipedia:Darifenacin "Wikipedia"
|
| skos:broader | |
| skos:relatedSynonym |
darifenacin,
(S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide,
C28H30N2O2,
[H][C@]1(CCN(CCc2ccc3OCCc3c2)C1)C(C(N)=O)(c1ccccc1)c1ccccc1,
InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1,
InChIKey=HXGBXQDTNZMWGS-RUZDIDTESA-N
|