| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Cyclin A is synthesized and associates with Cdc2 in G1. Cyclin dependent kinases are themselves catalytically inactive due to the fact that their active sites are blocked by a portion of the CDK molecule itself. Binding to their corresponding cyclin partner results in a conformational change that partially exposes the active site.
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| biopax3:xref | |
| biopax3:evidenceCode |