| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Although the enzyme catalysing retinal reduction in human enterocytes is not identified, the best candidate is RalR1. It is expressed in the intestine, has a basic pH optimum, and localises to the ER membrane where LRAT catalyses the next step in the pathway. However, RalR1 catalyses retinal reduction to retinol <i>in vitro</i> and uses NADPH as cofactor (Fierce et al. 2008).
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| biopax3:xref | |
| biopax3:evidenceCode |