48892Evidence3045

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Predicate	Object
rdf:type	biopax3:Evidence
biopax3:comment	Regulation of epithelial chloride flux, which is defective in patients with cystic fibrosis, may be mediated by phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR) by cyclic AMP-dependent protein kinase (PKA) or protein kinase C (PKC). CFTR regulates both HCO(3)(-) secretion and HCO(3)(-) salvage in secretory epithelia.
biopax3:xref	http://identifiers.org/pubmed/11562789, http://identifiers.org/pubmed/12403779, http://identifiers.org/pubmed/1377674
biopax3:evidenceCode	http://www.reactome.org/biopax/48892EvidenceCodeVocabulary1