| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
After dimerization of the PDGF-A and PDGF-B chains in the ER of producing cells, the dimers are proteolytically cleaved in the trans-Golgi network during protein maturation and secretion. The dibasic-specific proprotein convertase, furin, or related convertases are involved in the conversion of proPDGF forms to active PDGF forms.
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| biopax3:xref | |
| biopax3:evidenceCode |