48892Evidence1895

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Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	biopax3:Evidence
biopax3:comment	Tyrosine phosphorylated FRS2 recruits GRB2:SOS1 complex by means of the SH3 domain of GRB2, leading to RAS-MAP kinase activation. The FRS2:GRB2-mediated pathway plays a minor role in the activation of RAS-MAP kinase pathway compared to that mediated by FRS2:SHP2.
biopax3:xref	http://identifiers.org/pubmed/11353842, http://identifiers.org/pubmed/11447289, http://identifiers.org/pubmed/7559490, http://identifiers.org/pubmed/8780727, http://identifiers.org/pubmed/9182757
biopax3:evidenceCode	http://www.reactome.org/biopax/48892EvidenceCodeVocabulary1