| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Factor H (FH) binds to C3bBb, leading to displacement of Bb. Complement factor H-related protein 3 (FHR-3) has also been reported to bind C3Bb leading to inhibition of C3Bb C3 convertase activity (Fritsche et al. 2010). FH also acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b to iC3b.
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| biopax3:xref | |
| biopax3:evidenceCode |