| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
NF-kappaB is sequestered in the cytoplasm in a complex with inhibitor of NF-kappaB (IkB). Almost all NF-kappaB activation pathways are mediated by IkB kinase (IKK), which phosphorylates IkB resulting in dissociation of NF-kappaB from the complex. This allows translocation of NF-kappaB to the nucleus where it regulates gene expression.
|
| biopax3:xref | |
| biopax3:evidenceCode |