| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Before the cargo vesicle can fuse with target membrane, the COPII protein coat must be disassembled and its components released into cytosol. This uncoating is triggered by hydrolysis of the bound GTP to produce Sar1p-GDP, which has decreased affinity for the vesicle membrane. Disassociation of Sar1p-GDP from the membrane is followed by the release of the other COPII subunits.
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| biopax3:xref | |
| biopax3:evidenceCode |