| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
The polybasic region of STIM1 interacts with 2 aspartate residues in the C-terminal region of TRPC1 (Zeng et al. 2008, Huang et al. 2006). The STIM1:TRPC1 complex can form a tenary complex with ORAI1 (Ong et al. 2007, Jardin et al. 2008) and ORAI participates in function of STIM1:TRPC1 channels (Cheng et al. 2008, Cheng et al. 2011). As inferred from chicken DT40 cells, TRPC1 (and possibly other TRP channels) participates in store-operated calcium influx during signaling by the B cell receptor (Mori et al. 2002).
|
| biopax3:xref |
http://identifiers.org/pubmed/11901194,
http://identifiers.org/pubmed/16906149,
http://identifiers.org/pubmed/17224452,
http://identifiers.org/pubmed/17486119,
http://identifiers.org/pubmed/18326500,
http://identifiers.org/pubmed/18420269,
http://identifiers.org/pubmed/18843204,
http://identifiers.org/pubmed/18995841,
http://identifiers.org/pubmed/21408196,
http://identifiers.org/pubmed/22210847
|
| biopax3:evidenceCode |