| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
CD28 is capable of binding the Src homology 3 (SH3) domains of several proteins, including Grb2. The phospho-YMNM motif in CD28's cytoplasmic domain facilitates tandem SH2â??SH3 domain binding. Grb-2 has been shown to bind to the CD28 YMNM motif with additional SH3 domain binding to the diproline motif in the C-terminal portion of the cytoplasmic domain of CD28.
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| biopax3:xref | |
| biopax3:evidenceCode |