| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
PI3K enzyme bound to co-stimulatory protein CD28 catalyzes the phosphorylation of phosphatidylinositol 4,5-bisphosphate (PIP2) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). This PIP3 acts as a membrane anchor for the downstream proteins like PDK1 and PKB.
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| biopax3:xref | |
| biopax3:evidenceCode |