Source:http://www.reactome.org/biopax/48892BiochemicalReaction4704
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Authored: Garapati, P V, 2010-01-05,
DSCAM and DCC (Deleted in Colorectal Carcinoma) form a receptor complex in commissural axons in the absence of netrin1. They associate through a transmembrane interaction. The functional implication of this interaction is not known, but may allow DCC and DSCAM to contribute to other guidance pathways in a netrin1 independent fashion. It may serve as a way to hold DSCAM and DCC in a resting state, until netrin1 reaches a critical concentration at which both receptors are activated.,
Edited: Garapati, P V, 2010-01-05,
Reviewed: Clemens, JC, 2010-08-10
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Dscam binds Dcc
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