Source:http://www.reactome.org/biopax/48887TemplateReaction9
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Authored: Akkerman, JW, 2010-10-29,
Edited: Jupe, S, 2010-11-12,
Reviewed: Ouwehand, WH, 2010-11-12,
The Interferon alpha and beta genes are transcribed and translated yielding IFNA and IFNB which are secreted. This process is positively regulated by Interferon Regulatory Factor 1 and negatively regulated by Interferon Regulatory Factor 2, which compete for binding to the same regulatory element (Harada et al. 1989).
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Expression of Interferon-alpha and beta
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