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biopax3:comment |
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07,
Edited: Jassal, B, 2006-10-10 09:20:18,
Reviewed: Greene, LA, 2007-11-08 15:39:37,
Signalling through Shc adaptor proteins appears to be identical for both NGF and EGF. It leads to a fast, but transient, MAPK/ERK activation, which is insufficient to explain the prolonged activation of MAPK found in NGF-treated cells.
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