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Authored: Dall'Olio, GM, 2009-11-10,
Edited: Jassal, B, 2009-11-10,
Reviewed: Gagneux, P, 2010-04-16,
UDP-acetylglucosamine acts as a donor for the first two steps of the N-glycan precursor biosynthesis pathway, and is later used as a substrate for further modifications after the precursor has been attached to the protein. It is synthesized from fructose 6-phosphate, glutamine, acetyl-CoA, and UTP in four steps.
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Synthesis of UDP-N-acetyl-glucosamine
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