48887Pathway447

Source:http://www.reactome.org/biopax/48887Pathway447

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Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	biopax3:Pathway
biopax3:comment	Authored: May, B, 2009-06-02 00:51:49, Edited: May, B, 2009-06-02 00:51:49, Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31, Reviewed: Urano, F, 2010-04-30, Xbp-1 (S) binds the sequence CCACG in ER Stress Responsive Elements (ERSE, consensus sequence CCAAT (N)9 CCACG) located upstream from many genes. The ubiquitous transcription factor NF-Y, a heterotrimer, binds the CCAAT portion of the ERSE and together the IRE1-alpha: NF-Y complex activates transcription of a set of chaperone genes including DNAJB9, EDEM, RAMP4, p58IPK, and others. This results in an increase in protein folding activity in the ER.
biopax3:xref	http://identifiers.org/pubmed/14559994, http://identifiers.org/pubmed/16461360, http://identifiers.org/pubmed/16539657, http://identifiers.org/pubmed/17612490, http://identifiers.org/pubmed/18664523, urn:biopax:UnificationXref:REACTOME DATABASE ID_381038, urn:biopax:UnificationXref:REACTOME_REACT_18273_3
biopax3:dataSource	http://www.reactome.org/biopax/48887Provenance1, urn:biopax:Provenance:reactome_hm_41
biopax3:displayName	Activation of Chaperone Genes by XBP1(S)
biopax3:organism	http://identifiers.org/taxonomy/9606
biopax3:pathwayComponent	http://www.reactome.org/biopax/48887TemplateReaction55, http://www.reactome.org/biopax/48887TemplateReaction56, http://www.reactome.org/biopax/48887TemplateReaction57, http://www.reactome.org/biopax/48887TemplateReaction58, http://www.reactome.org/biopax/48887TemplateReaction59, http://www.reactome.org/biopax/48887TemplateReaction60, http://www.reactome.org/biopax/48887TemplateReaction61, http://www.reactome.org/biopax/48887TemplateReaction62, http://www.reactome.org/biopax/48887TemplateReaction63, http://www.reactome.org/biopax/48887TemplateReaction64, http://www.reactome.org/biopax/48887TemplateReaction65, http://www.reactome.org/biopax/48887TemplateReaction66, http://www.reactome.org/biopax/48887TemplateReaction67, http://www.reactome.org/biopax/48887TemplateReaction68, http://www.reactome.org/biopax/48887TemplateReaction69, http://www.reactome.org/biopax/48887TemplateReaction70, http://www.reactome.org/biopax/48887TemplateReaction71, http://www.reactome.org/biopax/48887TemplateReaction72, http://www.reactome.org/biopax/48887TemplateReaction73, http://www.reactome.org/biopax/48887TemplateReaction74, http://www.reactome.org/biopax/48887TemplateReaction75, http://www.reactome.org/biopax/48887TemplateReaction76, http://www.reactome.org/biopax/48887TemplateReaction77, http://www.reactome.org/biopax/48887TemplateReaction78, http://www.reactome.org/biopax/48887TemplateReaction79, http://www.reactome.org/biopax/48887TemplateReaction80, http://www.reactome.org/biopax/48887TemplateReaction81, http://www.reactome.org/biopax/48887TemplateReaction82, http://www.reactome.org/biopax/48887TemplateReaction83, http://www.reactome.org/biopax/48887TemplateReaction84, http://www.reactome.org/biopax/48887TemplateReaction85, http://www.reactome.org/biopax/48887TemplateReaction86, http://www.reactome.org/biopax/48887TemplateReaction87, http://www.reactome.org/biopax/48887TemplateReaction88, http://www.reactome.org/biopax/48887TemplateReaction89, http://www.reactome.org/biopax/48887TemplateReaction90, http://www.reactome.org/biopax/48887TemplateReaction91, http://www.reactome.org/biopax/48887TemplateReaction92, http://www.reactome.org/biopax/48887TemplateReaction93, http://www.reactome.org/biopax/48887TemplateReaction94, http://www.reactome.org/biopax/48887TemplateReaction95, http://www.reactome.org/biopax/48887TemplateReaction96, http://www.reactome.org/biopax/48887TemplateReaction97, http://www.reactome.org/biopax/48887TemplateReaction98, http://www.reactome.org/biopax/48887TemplateReaction99
biopax3:pathwayOrder	http://www.reactome.org/biopax/48887PathwayStep2222, http://www.reactome.org/biopax/48887PathwayStep2190, http://www.reactome.org/biopax/48887PathwayStep2221, http://www.reactome.org/biopax/48887PathwayStep2225, http://www.reactome.org/biopax/48887PathwayStep2196, http://www.reactome.org/biopax/48887PathwayStep2217, http://www.reactome.org/biopax/48887PathwayStep2224, http://www.reactome.org/biopax/48887PathwayStep2206, http://www.reactome.org/biopax/48887PathwayStep2194, http://www.reactome.org/biopax/48887PathwayStep2195, http://www.reactome.org/biopax/48887PathwayStep2209, http://www.reactome.org/biopax/48887PathwayStep2210, http://www.reactome.org/biopax/48887PathwayStep2213, http://www.reactome.org/biopax/48887PathwayStep2185, http://www.reactome.org/biopax/48887PathwayStep2205, http://www.reactome.org/biopax/48887PathwayStep2198, http://www.reactome.org/biopax/48887PathwayStep2208, http://www.reactome.org/biopax/48887PathwayStep2218, http://www.reactome.org/biopax/48887PathwayStep2215, http://www.reactome.org/biopax/48887PathwayStep2212, http://www.reactome.org/biopax/48887PathwayStep2220, http://www.reactome.org/biopax/48887PathwayStep2226, http://www.reactome.org/biopax/48887PathwayStep2203, http://www.reactome.org/biopax/48887PathwayStep2228, http://www.reactome.org/biopax/48887PathwayStep2219, http://www.reactome.org/biopax/48887PathwayStep2187, http://www.reactome.org/biopax/48887PathwayStep2201, http://www.reactome.org/biopax/48887PathwayStep2186, http://www.reactome.org/biopax/48887PathwayStep2216, http://www.reactome.org/biopax/48887PathwayStep2204, http://www.reactome.org/biopax/48887PathwayStep2211, http://www.reactome.org/biopax/48887PathwayStep2229, http://www.reactome.org/biopax/48887PathwayStep2188, http://www.reactome.org/biopax/48887PathwayStep2192, http://www.reactome.org/biopax/48887PathwayStep2193, http://www.reactome.org/biopax/48887PathwayStep2214, http://www.reactome.org/biopax/48887PathwayStep2223, http://www.reactome.org/biopax/48887PathwayStep2227